PATENTS
PUBLICATIONS
- Biodegradable chitosan-PEG compositions and methods of use. United State Patent 8,663,686 (Awarded March 4, 2014).
- Alginate Based Nanofibers and Related Scaffolds. United State Patent 8,147,858 (Awarded April 3, 2012).
PUBLICATIONS
- Acharya, R., Tettey, F., Gupta, A., Sharma, K. R., Parajuli, N., & Bhattarai, N. (2024). Bioinspired synthesis and characterization of zinc oxide nanoparticles and assessment of their cytotoxicity and antimicrobial efficacy. Discover Applied Sciences, 6(3), 1-17
- Tettey, F., Saudi, S., Davies, D., Shrestha, S., Johnson, K., Fialkova, S., ... & Bhattarai, N. (2023). Fabrication and characterization of Zn particle incorporated fibrous scaffolds for potential application in tissue healing and regeneration. ACS Applied Materials & Interfaces, 15(42), 48913-48929.
- Tettey, F., Siler-Dearring, J., Moody, A., & Bhattarai, N. (2023). Preparation and characterization of poliglecaprone-incorporated polycaprolactone composite fibrous scaffolds. Fibers, 11(10), 82.
- Sapkota, T., Shrestha, B. K., Shrestha, S., & Bhattarai, N. (2023). Chitin Nanofibrils Enabled Core–Shell Microcapsules of Alginate Hydrogel. Nanomaterials, 13(17), 2470.
- Saudi, S., Jun, S., Fialkova, S., Surendran, V., Chandrasekaran, A., Bhattarai, S. R., ... & Bhattarai, N. (2023). Incorporating nanoconfined chitin‐fibrils in poly (ε‐caprolactone) membrane scaffolds improves mechanical and chemical properties for biomedical application. Journal of Biomedical Materials Research Part A, 111(8), 1185-1199.
- Parupelli, S. K., Saudi, S., Bhattarai, N., & Desai, S. (2023). 3D printing of PCL-ceramic composite scaffolds for bone tissue engineering applications. Int. J. Bioprinting, 9(2).
- Mandal, A. K., Katuwal, S., Tettey, F., Gupta, A., Bhattarai, S., Jaisi, S., ... & Parajuli, N. (2022). Current research on zinc oxide nanoparticles: Synthesis, characterization, and biomedical applications. Nanomaterials, 12(17), 3066.
- Tatum, S. D., Saudi, S., Tettey, F., Bhandari, R. K., & Bhattarai, N. A. (2021). Novel hydrogel-bronchial epithelial cell spheroids for toxicological evaluation. Biomed. Sci. Instrum, 57(4).
- Bhattarai, S. R., Saudi, S., Khanal, S., Aravamudhan, S., Rorie, C. J., & Bhattarai, N. (2021). Electrodynamic assisted self-assembled fibrous hydrogel microcapsules: a novel 3D in vitro platform for assessment of nanoparticle toxicity. RSC advances, 11(9), 4921-4934.
- Saudi, S., Bhattarai, S. R., Adhikari, U., Khanal, S., Sankar, J., Aravamudhan, S., & Bhattarai, N. (2020). Nanonet-nano fiber electrospun mesh of PCL–chitosan for controlled and extended release of diclofenac sodium. Nanoscale, 12(46), 23556-23569.
- Khanal, S., Bhattarai, S. R., Sankar, J., Bhandari, R. K., Macdonald, J. M., & Bhattarai, N. (2019). Nano-fibre integrated microcapsules: A nano-in-micro platform for 3D cell culture. Scientific Reports, 9(1), 13951.
- Adhikari, U., An, X., Rijal, N., Hopkins, T., Khanal, S., Chavez, T., ... & Pixley, S. K. (2019). Embedding magnesium metallic particles in polycaprolactone nanofiber mesh improves applicability for biomedical applications. Acta biomaterialia, 98, 215-234.
- Parupelli, S. K., Aljohani, A., Desai, S., Khanal, S., & Bhattarai, N. (2019). Direct jet printing and characterization of calcium alginate microcapsules for biomedical applications. In IIE Annual Conference. Proceedings (pp. 300-305). Institute of Industrial and Systems Engineers (IISE).
- Rijal, N. P., Adhikari, U., Khanal, S., Pai, D., Sankar, J., & Bhattarai, N. (2018). Magnesium oxide-poly (ε-caprolactone)-chitosan-based composite nanofiber for tissue engineering applications. Materials Science and Engineering: B, 228, 18-27.
- Tikunov, A. P., Shim, Y. S., Bhattarai, N., Siler, S. Q., Soldatow, V., LeCluyse, E. L., ... & Macdonald, J. M. (2017). Dose-response in a high density three-dimensional liver device with real-time bioenergetic and metabolic flux quantification. Toxicology in Vitro, 45, 119-127.
- Thompson, Z., Rahman, S., Yarmolenko, S., Sankar, J., Kumar, D., & Bhattarai, N. (2017). Fabrication and characterization of magnesium ferrite-based PCL/Aloe vera nanofibers. Materials, 10(8), 937.
- Rahman, S., Carter, P., & Bhattarai, N. (2017). Aloe vera for tissue engineering applications. Journal of functional biomaterials, 8(1), 6.
- Salas, C., Thompson, Z., & Bhattarai, N. (2017). Electrospun chitosan fibers. In Electrospun nanofibers (pp. 371-398). Woodhead Publishing.
- Rijal, N. P., Adhikari, U., & Bhattarai, N. (2017). Production of electrospun chitosan for biomedical applications. In Chitosan Based Biomaterials Volume 1 (pp. 211-237). Woodhead Publishing.
- Adhikari, U., Rijal, N. P., Khanal, S., Pai, D., Sankar, J., & Bhattarai, N. (2016). Magnesium incorporated chitosan based scaffolds for tissue engineering applications. Bioactive Materials. doi:10.1016/j.bioactmat.2016.11.003
- Khanal, S.; Adhikari, U.; Rijal, N.; Bhattarai, S.; Sankar, J.; Bhattarai, N. Ph-responsive plga nanoparticle for controlled payload delivery of diclofenac sodium. Journal of Functional Biomaterials 2016, 7, 21.
- Mahoney, C.; Conklin, D.; Waterman, J.; Sankar, J.; Bhattarai N. "Electrospun Nanofibers of Poly(ε-caprolactone)/Depolymerized Chitosan for Respiratory Tissue Engineering Applications", Journal of Biomaterials Science, Polymer Edition, DOI:10.1080/09205063.2016.11444542 (2016)
- Bhattarai, N; Bhattarai, S.R. "Smart Theranostic Nano Materials: Recent Progress from Bench to Bedside Translation", Journal of Nanomedicine Research, 2 (2015)-5
- Rijal, N.P,; Adhikari, U.; Bhattarai,N. "Production of Electrospun Chitosan for Biomedical Applications", Chitosan-based biomaterials Vol 1, Elsevier 2015 (under final review).
- Thompson, Z., Rijal, N., Jarvis, D., Edwards, A., Bhattarai, N. Synthesis of Keratin-based Nanofiber for Biomedical Engineering. J. Vis. Exp. (), e53381, doi:10.3791/53381 (2015)-In Press.
- Rahman, S. M., Mahoney, C., Sankar, J., Marra, K. G. & Bhattarai, N. 2016. Synthesis and characterization of magnesium gluconate contained poly(lactic-co-glycolic acid)/chitosan microspheres. Materials Science and Engineering: B, 203, 59-66.
- Boakye, M.A.D.; Rijal, N.P.; Adhikari, U.; Bhattarai, N. Fabrication and Characterization of Electrospun PCL-MgO-Keratin-Based Composite Nanofibers for Biomedical Applications. Materials 2015, 8, 4080-4095.
- Angela Edwards, *David Jarvis, Sarah Pixley, and Naryan Bhattarai. Poly(caprolactone)/keratin-based composite nanofibers for biomedical applications. Journal of Biomedical Materials Research: Part B 103(2015)21–30
- Roman Blunt and Narayan Bhattarai “Natural polysaccharide-based hydrogels for controlled localized drug delivery, In Applications of Hydrogels in Drug Delivery and Biosensors Edited by Sheereen Majd and Lifeng Kang, World Scientific Publishing Company 2014 (under review).
- Remant Bahadur K.C., Bindu Thapa, Narayan Bhattarai “Gold Nanoparticles Based Gene Delivery: Promises and Challenges”. Nanotechnology Reviews (2013)1–13.
- Princeton Carter and Narayan Bhattarai “Bioscaffolds: Fabrication and Performance”, In Engineered Biomimicry Edited by Akhlesh Lakhtakia and Raúl José Martín-Palma, Elsevier Inc. 2013.
- Christopher Mahoney, Matthew B. Mccullough, Jagannathan Sankar and Narayan Bhattarai “Nanofibrous Structure of Chitosan for Biomedical Applications”, Journal of Nanomedicine and Biotherapeutics Discovery, 2 (2012) 102.
- Stephen J. Florczyk; Matthew Leung; Soumen Jana; Zhensheng Li; Narayan Bhattarai; Jerry I. Huang; Richard A. Hopper; Miqin Zhang “Enhanced bone tissue formation by alginate gel-assisted cell seeding in porous ceramic scaffolds and sustained release of growth factor” Journal of Biomedical Materials Research - Part A: 00A: 000-000, 2012.
- Narayan Bhattarai and Shanta R Bhattarai “Theranostic Nanoparticles: A Recent Breakthrough in Nanotechnology” Editorials: Journal of Nanomedicine and Nanotechnology 3 (2012) 6.
- *Sonja Turner and Narayan Bhattarai “From Macromolecule to Nanofiber: Electrospinning Just the Technique for the Job”, 119th ASEE Annual Conference & Exposition (San Antonio, TX), June 10-13, 2012.
- Ashleigh Cooper, Narayan Bhattarai, Forrest Kievit, *Michael Rossol, and Miqin Zhang “Electrospinning of chitosan derivative nanofibers with structural stability in an aqueous environment", Physical Chemistry Chemical Physics, 13(2011), 9969-9972.
- Ashleigh Cooper, Narayan Bhattarai, and Miqin Zhang “Fabrication and cellular compatibility of aligned chitosan-PCL fibers for nerve tissue regeneration", Carbohydrate Polymers, 85 (2011), 149-156.
- Forrest M. Kievit, Omid Veiseh, Chen Fang, Narayan Bhattarai, Donghoon Lee, Richard Ellenbogen, and Miqin Zhang “Chlorotoxin labeled magnetic nanovectors for targeted gene delivery to glioma", ACS Nano, 4 (2010), 4587-4594.
- Ashleigh Cooper, Soumen Jana, Narayan Bhattarai, and Miqin Zhang “Aligned chitosan-based nanofibers for enhanced myogenesis", Journal of Materials Chemistry 20 (2010) 8904
- C. Sun, *K. Du, Chen Fang, Narayan Bhattarai, Omid Veiseh, Forrest Kievit, Zach Stephen, Donghoon Lee, Richard Ellenbogen, Boddy Ratner, and Miqin Zhang “PEG-mediated synthesis of highly dispersive multifunctional superparamagnetic nanoparticles: their physicochemical properties and function in vivo" ACS Nano, 4 (2010), 2402.
- Narayan Bhattarai, Jonathan Gunn, Miqin Zhang “Chitosan-based hydrogels for controlled, localized drug delivery” Advanced Drug Delivery Review 62 (2010) 83. (Most downloaded advanced drug delivery reviews articles in January 2010)
- Narayan Bhattarai, Zhensheng Li, Jonathan Gunn, Matthew Leung, Ashleigh Cooper, Dennis Edmondson, Omid Veiseh, Ming-Hong Chen, Yong Zhang, Richard G. Ellenbogen, Miqin Zhang “Natural-Synthetic Polyblend Nanofibers for Biomedical Applications” Advanced Materials 21(2009) 2792.
- Omid Veiseh, Conroy Sun, Chen Fang, Narayan Bhattarai, Jonathan Gunn, Forrest Kievit, Kim Du, Barbara Pullar, Donghoon Lee, Richard G. Ellenbogen, Jim Olson, and Miqin Zhang “Specific Targeting of Brain Tumors with an Optical/Magnetic Resonance Imaging Nanoprobe across the Blood-Brain Barrier” Cancer Research 69(2009) 6200.
- Forrest M. Kievit, Omid Veiseh, Narayan Bhattarai, Chen Fang, Jonathan W. Gunn, Donghoon Lee, Richard G. Ellenbogen, James M. Olson Miqin Zhang “PEI-PEG-Chitosan-Copolymer-Coated Iron Oxide Nanoparticles for Safe Gene Delivery: Synthesis, Complexation, and Transfection” Advanced Functional Materials 19 (2009) 2244.
- Chen Fang, Narayan Bhattarai, Conroy Sun, Miqin Zhang “Functionalized Nanoparticles with Long-Term Stability in Biological Media” Small 5(2009) 1637.
- Dennis Edmondson, Narayan Bhattarai, Soumen Jana, Abraham Kim, Miqin Zhang “Design and evaluation of a nanoscale differential tensile test device for nanofibers” Applied Physics Letters 94 (2009) 103101.
- Shanta Raj Bhattarai, Remant Bahadur K.C., Santosh Aryal, Narayan Bhattarai, Sun Young Kim, Ho Keun Yi, Pyoung Han Hwang, Hak Yong Kim “Hydrophobically modified chitosan/gold nanoparticles for DNA delivery” Journal of Nanoparticle Research 10 (2008)151.
- Narayan Bhattarai and Miqin Zhang, “Controlled synthesis and structural stability of alginate based nanofibers” Nanotechnology 18 (2007) 455601.
- Shanta Raj Bhattarai, Sun Young Kim, Ho-Keun Yi, Narayan Bhattarai, Hak Yong Kim, Pyoung Han Hwang. “Amphiphilic Triblock Copolymer Poly (p-Dioxanone-co-L-Lactide)-block- Poly (ethylene glycol), Enhancement of Gene Expression and Inhibition of Lung Metastasis by Aerosol Delivery” Gene Therapy 14 (2007) 476.
- Narayan Bhattarai, Zhensheng Li, Dennis Edmondson, and Miqin Zhang "Alginate-Based Nanofibrous Scaffolds: Structural, Mechanical and Biological Properties", Advanced Materials, 18 (2006)1463.
- Naryan Bhattarai, Hassna R. Ramay, S. H. Chou, and Miqin Zhang "Chitosan and lactic acid grafted chitosan nanoparticles as carriers for prolonged drug delivery", International Journal of Nanomedicine 2(2006).
- Remant B.K.C., Santosh Aryal, Shanta Raj Bhattarai, Narayan Bhattarai, Chi Hun Kim, and Hak Yong Kim “Stabilization of gold nanoparticles by hydrophobically-modified polycations” Journal of Biomaterial Science; Polymer Edition 17 (2006) 579.
- *Dong Il Cha, Hak Yong Kim, KH Lee, Narayan Bhattarai “Mechanical behaviors and characterization of electrospun polysulfone/polyurethane blend nonwovens” Macromolecular Research, 3(2006) 331-337.
- Shanta Raj Bhattarai, Narayan Bhattarai, Periasamy Viswanathamurthi, Ho Keun Yi, Pyoung Han Hwang, Hak Yong Kim. “Hydrophilic nanofibrous structure of polylactide; fabrication and cell affinity” Journal of Biomedical Materials Research 78A (2006)247.
- Omid Veiseh, Conroy Sun, Jonathan Gunn, Nathan Kohler, Patrik Gabikian, Donghoon Lee, Narayan Bhattarai, Richard Ellenbogen, Raymond Sze, Andrew Hallahan, Jim Olson, and Miqin Zhang "An optical and MRI multifunctional nanoprobe for targeting gliomas” Nano Letters, 5 (2005)1003.
- Narayan Bhattarai, Dennis Edmondson, Omid Veiseh, Frederick A. Matsen and Miqin Zhang “Electrospunn chitosan-based nanofibers and their cellular compatibility” Biomaterials 26(2005) 6176.
- Narayan Bhattarai, Frederick A. Matsen and Miqin Zhang “PEG-grafted Chitosan as an InjectableThermoreversible Hydrogel” Macromolecular Bioscience 5(2005) 107.
- Narayan Bhattarai, Hassna R. Ramay, Jonathan Gunn, Frederick A. Matsen, Miqin Zhang. “PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release” Journal of Controlled Release 103 (2005) 609. (Top 2nd article within the articles published in Journal of Controlled Release, 2005).
- Narayan Bhattarai, Myung Seob Khil, Hak Yong Kim, Kwan Woo Kim. “Thermal Decomposition Kinetics of copolymers Derived from p-dioxanone, L-lactide and Poly (ethylene glycol)” Fibers and Plymers 5(2004) 289.
- Shanta Raj Bhattarai, Narayan Bhattarai, Ho Keun Yi, Pyong Han Hwang, Dong Il Cha, Hak Yong Kim “Novel biodegradable electrospun membrane; Scaffold for tissue engineering” Biomaterials 25( 2004) 2595.
- Narayan Bhattarai, Wen Ying Jiang, Hak Yong Kim, Douck Rae Lee, Soo “Synthesis and hydrolytic degradation of a random copolymer derived from 1,4-dioxan-2-one and glycolide” Journal of Polymer Science Part B 42(2004) 2558.
- Periasamy Viswanathamurthi, Narayan Bhattarai, Hak Yong Kim, Dong Ill Cha and Douck Rae Lee. “Preparation and morphology of palladium oxide fiber via electrospinning” Materials Letters 26(2004) 3368.
- Periasamy Viswanathamurthi, Narayan Bhattarai, Hak Yong Kim, Myung Seob Khil, Douk Rae Lee. “Nanofiers of GeO2: Preparation, morphology and photoluminescence property” Journal of Chemical Physics 121(2004) 441.
- Periasamy Viswanathamurthi, Narayan Bhattarai, Chul Ki Kim, Hak Yong Kim and Douck Rae Lee. “Ruthenium doped TiO2 fibers by electrospinning ”Inorganic Chemistry Communications 7( 2004) 79.
- Narayan Bhattarai, Shanta Raj Bhattarai, Ho Keun Yi, Jong Chang Lee, Myung Seob Khil, Pyong Han Hwang, Hak Yong Kim “Novel polymeric micelles of amphiphilic triblock copolymer poly(p-dioxanone-co-L-lactide)-block- poly(ethylene glycol)” Pharmaceutical Research 12( 2003) 2021.
- Narayan Bhattarai, Dong Il Cha, Shanta Raj Bhattarai, Myung Seob Khil, Hak Yong Kim. “Biodegradable electrospun mat; Novel block copolymer poly(p-dioxanone-co-L-lactide)-block-poly(ethylene glycol)” Journal of Polymer Science Part B: Polymer Physics 41(2003) 1955.
- Narayan Bhattarai, Hak Yong Kim, Douk Rae Lee, Soo-Jin Park “Synthesis and characterization of ABA type tri-block copolymers derived from p-dioxanone, L-lactide and poly(ethylene glycol)” Polymer International 52(2003) 6.
- Narayan Bhattarai, Shanta Raj Bhattarai, Myung Seob Khil, Douk Rae Lee, Hak Yong Kim “Aqueuos solution properties of amphiphilic triblock copolymer poly(p-dioxanone-co-L-lactide)-block-poly(ethylene glycol)” European Polymer Journal 39(2003) 1603.
- Myung Seob Khil, *Dong Il Cha, Hak Yong Kim, In Shik Kim, Narayan Bhattarai “Electrospun nanofibrous polyurethane membrane as wound dressing” Journal of Biomedical Material Research 67B(2003) 675.
- Narayan Bhattarai, Hak Yong Kim, *Dong Il Cha, Douk Rae Lee and Dong Il Yoo “Nonisothermal crystallization and melting behavior of the copolymer derived from p-dioxanone and poly(ethylene glycol)” European Polymer Journal, 39(2003)1365.
- Yong Tang Jia, Hak Yong Kim, Jian Gong, Douk Rae Lee, Bin Ding, Narayan Bhattarai “Synthesis and characterization of ABA type block copolymer of trimethylene carbonate & e-Caprolatctone” Polymer International 53(2003) 312.
- Narayan Bhattarai, Hak Yong Kim and Douk Rae Lee “Thermogravimetric study of copolymers derived from p-dioxanone, L-lactide and poly (ethylene glycol)” Polymer Degradation and Stability 78(2002) 423.
- Hak Yong Kim, Periasamy Viswanathamurthi, Narayan Bhattarai and Bin Ding “Electrospinning: A novel method for metal oxide fibers” Focus in Nanotechnology Research Nova Science Publishers Inc. Hauppauge, NY 2004.